Upper and lower respiratory tract infections, Urinary tract infections, Gonococcal urethritis, Acute otitis media, Skin & soft tissue infection.

Antibacterial

Rofixim® Capsule: 1 or 2 capsules (200 mg -400 mg) as a single dose or in 2 divided doses daily for 7-14 days, according to the severity of infection. Rofixim® Powder for Suspension: Child dose: 8 mg/kg daily as a single dose or in two divided doses for 7-14 days according to the severity of infection or for age; 1/2-1 years: 3.75 ml or 75 mg; 1-4 years: 5 ml or 100 mg; 5-10 years: 10 ml or 200 mg; 11-12 years: 15 ml or 300 mg; above 12 years: adult dose.

Patients with known hypersensitivity to cephalosporin group of drugs.

Cefixime is generally well tolerated. The majority of adverse reactions in clinical trials were mild and self-limiting in nature. Gastro-intestinal disturbances: diarrhea (if severe diarrhea occurs, Rofixim® should be discontinued), changes in the colour of stool, nausea, abdominal pain, dyspepsia, vomiting, flatulence have been reported; Central nervous system disturbances: headache, dizziness; Others: hypersensitivity reactions which usually subsided upon discontinuation of therapy; in frequents and reversible haemotological changes; elevation of serum amylase.

Rofixim® should be prescribed with caution in individuals with a history of gastrointestinal diseases, particularly colitis. Dosage adjustment is only necessary in severe renal failure (creatinine clearance <20 ml. min-1).

Store in a cool & dry place, away from direct light.