Montelukast is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Montelukast comes as a tablet, a chewable tablet, flash tablet and granules to take by mouth. Montelukast is usually taken once a day with or without food. Montelukast is a CysLT1 antagonist; it blocks the action of leukotrieneD4 (and secondary ligands LTC4 and LTE4) on the cysteinyl leukotriene receptor CysLT1 in the lungs and bronchial tubes by binding to it. This reduces the bronchoconstriction otherwise caused by the leukotriene and results in less inflammation.
Because of its method of operation, it is not useful for the treatment of acute asthma attacks. Again because of its very specific mechanism of action, it does not interact with other asthma medications such as theophylline.
Each film-coated tablet contains Montelukast BP 10 mg & Montelukast BP 10 mg
15 years & older- 10 mg tab 6 years – 14 years- 5 mg chewable tab 2-5 years- 4 mg chewable tablet 6-23 months- 4mg oral granules
Generally, Montelukast is well-tolerated. Side effects include
• Abdominal pain
Montelukast is contraindicated to patients with hypersensitivity to any component of this product.
Pregnancy category B
It is recommended to only use this medication during pregnancy if necessary.
• Phenobarbital (Luminal, Solfoton); or
• Rifampin (Rifadin, Rifater, Rifamate, Rimactane)
The most frequently occurring adverse experiences were consistent with the safety profile and included abdominal pain, somnolence, thirst, headache, vomiting, and psychomotor hyperactivity.
Store in a cool & dry place, protect from light & moisture.
Keep out of reach of children.
XyfloTM 10 Tablet: Each box contains 3 X 10’s film-coated tablets in Alu-Alu blister pack.
XyfloTM 5Tablet: Each box contains 3 X 10’s Chewable tablets in Alu-Alu blister pack.